EIF2C2 (Eukaryotic translation initiation factor 2C, 2, AGO2, Argonaute2, eIF2C 2, eIF-2C 2, Eukaryotic translation initiation factor 2C 2, hAgo2, PAZ Piwi domain protein, PPD, Protein argonaute-2, Protein slicer, Q10) | US Biological E2237-26 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

EIF2C2 (Eukaryotic translation initiation factor 2C, 2, AGO2, Argonaute2, eIF2C 2, eIF-2C 2, Eukaryotic translation initiation factor 2C 2, hAgo2, PAZ Piwi domain protein, PPD, Protein argonaute-2, Protein slicer, Q10)

catalog :

E2237-26

quantity :

100 ul

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

10g170(C34C6)

reactivity :

human

product information

Catalog Number :

E2237-26

Product wo Prefix :

Host :

rabbit

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

10g170(C34C6)

Isotype :

IgG

Desc1 :

Small non-coding RNAs are important regulators of gene expression in higher eukaryotes. Several classes of small RNAs, including short interfering RNAs (siRNAs), microRNAs (miRNAs) and Piwi-interacting RNAs (piRNAs), have been identified. MicroRNAs are about 21 nucleotides in length and have been implicated in many cellular processes such as development, differentiation and stress response. MicroRNAs regulate gene expression by modulating mRNA translation or stability. MicroRNAs function together with the protein components in the complexes called micro-ribonucleoproteins (miRNPs). Among the most important components in these complexes are Argonaute proteins. There are four members in the mammalian Argonaute family and only Argonaute 2 (Ago2) possesses the Slicer endonuclease activity. Argonaute proteins participate in the various steps of microRNA-mediated gene silencing such as repression of translation and mRNA turnover. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Immunoprecipitation: 1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mk Mo Rt

Immunogen :

Synthetic peptide corresponding to mouse EIF2C2.

Specificity :

Recognizes endogenous levels of total mouse EIF2C2 at ~97kD. Species Crossreactivity: human, rat and monkey

Purity :

Purified

Form :

Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, <0.02% sodium azide, 50% glycerol.

Concentration :

Not Determined

Desc2 :

Product Type: Mab Isotype: IgG Clone No: 10g170(C34C6) Host: rabbit Source: mouse Concentration: Not Determined Form: Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, <0.02% sodium azide, 50% glycerol. Purity: Purified Immunogen: Synthetic peptide corresponding to mouse EIF2C2. Specificity: Recognizes endogenous levels of total mouse EIF2C2 at ~97kD. Species Crossreactivity: human, rat and monkey Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

IP WB

Storage Temperature :

-20°C

Reference :

1. Peters, L. and Meister, G. (2007) Mol Cell 26, 611-23. 2. Filipowicz, W. et al. (2008) Nat Rev Genet 9, 102-14. 3. Caplen, N.J. et al. (2001) Proc Natl Acad Sci USA 98, 9742-7. 4. Mourelatos, Z. et al. (2002) Genes Dev 16, 720-8. 5. Girard, A. et al. (2006) Nature 442, 199-202.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/0/E2237-26_1.jpg