DNA, ds | US Biological D3878-13B product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

DNA, ds

catalog :

D3878-13B

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AE-2

product information

Catalog Number :

D3878-13B

Product wo Prefix :

DNA, ds

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ug

Clone # USB :

AE-2

Isotype :

IgG3

Desc1 :

dsDNA (double stranded deoxyribonucleic acid) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry: Paraformaldehyde fixed or frozen tissue and formalin fixed paraffin-embedded tissue sections. Optimal dilutions to be determined by the researcher. Positive Control: Tonsil tissue Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

Double-stranded DNA

Immunogen :

Nuclei of Raji Burkitt’s lymphoma cells

Specificity :

Recognizes double stranded DNA expressed in the nucleus of human cells. Produces a homogeneous staining pattern in the nucleus of normal and malignant cells.

Purity :

Purified

Form :

Supplied as a liquid in PBS, 0.05% sodium azide.

Concentration :

~0.1mg/ml

Desc2 :

Product Type: Mab Isotype: IgG3 Clone No: AE-2 Host: mouse Source: human Concentration: ~0.1mg/ml Form: Supplied as a liquid in PBS, 0.05% sodium azide. Purity: Purified Immunogen: Nuclei of Raji Burkitt’s lymphoma cells Specificity: Recognizes double stranded DNA expressed in the nucleus of human cells. Produces a homogeneous staining pattern in the nucleus of normal and malignant cells. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FC IC IHC

Storage Temperature :

4°C Do Not Freeze

Reference :

1.Epstein, A.L. and Clevenger, C.V., Identification of nuclear antigens in human cells by immunofluorescence, immunoelectron microscopy, and immuno-biochemical methods using monoclonal antibodies. In: Progress on nonhistone protein research, Vol. 1, Isaac Bekhor, ed., 1985, CRC Press, Boca Raton, FL, pp 117-137