DcR1 (TRAIL-R3, TRID, LIT, TRAIL Decoy Receptor1) | US Biological D1499-04 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

DcR1 (TRAIL-R3, TRID, LIT, TRAIL Decoy Receptor1)

catalog :

D1499-04

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6D346 (HS301)

reactivity :

human

product information

Catalog Number :

D1499-04

Product wo Prefix :

DcR1 (TRAIL-R3, TRID, LIT, TRAIL Decoy Receptor1)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ug

Clone # USB :

6D346 (HS301)

Isotype :

IgG1

Desc1 :

DcR1 is a 65kD GPI-anchored member of the TNFR superfamily (TNFRSF10C) also known as TRAIL-R3, TRID, CD263, and LIT. Although not expressed by most tumors, DcR1 is expressed at low levels on normal tissues, acting as a TRAIL decoy receptor, thus inhibiting apoptosis. DcR1 is termed a decoy receptor, as it does not have a functional death domain to induce apoptosis following TRAIL ligation. Applications: Suitable for use in Flow Cytometry and Immunocytochemistry. For Western Blot use D1499-04H. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Recombinant protein corresponding to human TRAIL-R3 (DcR1).

Specificity :

Recognizes human TRAIL-R3. Does not cross-react with human TRAIL-R1, -R2 or -R4.

Purity :

Purified

Form :

Supplied as a liquid in PBS, 0.05% sodium azide.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 6D346 Host: mouse Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in PBS, 0.05% sodium azide. Purity: Purified Immunogen: Recombinant protein corresponding to human TRAIL-R3 (DcR1). Specificity: Recognizes human TRAIL-R3. Does not cross-react with human TRAIL-R1, -R2 or -R4. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FC IC

Storage Temperature :

-20°C

Reference :

1.B. Washburn, et al.; J. Immunol. 170, 1814 (2003) 2. P. Secchiero, et al.; Blood 103, 517 (2004) 3. T.M. Ganten, et al.; Cell Death Differ. 11 Suppl 1, S86 (2004) 4. T. Wachter, et al.; J. Biol. Chem. 279, 52824 (2004)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/7/D1499-04_1.jpg