CDKN2A (Cyclin-dependent Kinase Inhibitor 2A, Isoforms 1/2/3, Cyclin-dependent Kinase 4 Inhibitor A, CDK4I, Multiple Tumor Suppressor 1, MTS-1, p16-INK4a, p16-INK4, p16INK4A, CDKN2, MTS1) | US Biological C8471-65R product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

CDKN2A (Cyclin-dependent Kinase Inhibitor 2A, Isoforms 1/2/3, Cyclin-dependent Kinase 4 Inhibitor A, CDK4I, Multiple Tumor Suppressor 1, MTS-1, p16-INK4a, p16-INK4, p16INK4A, CDKN2, MTS1)

catalog :

C8471-65R

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

C8471-65R

Product wo Prefix :

CDKN2A (Cyclin-dependent Kinase Inhibitor 2A, Isoforms 1/2/3, Cyclin-dependent Kinase 4 Inhibitor A, CDK4I, Multiple Tumor Suppressor 1, MTS-1, p16-INK4a, p16-INK4, p16INK4A, CDKN2, MTS1)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

CDKN2A acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 0.1-1ug/ml, observed in lysates of the cell lines A431 and HeLa on ~16-18kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Synthetic peptide corresponding to C-HARIDAAEGPSDIPD, from human CDKN2A, at C-terminal (NP_000068.1, NP_001182061.1).

Specificity :

Recognizes human CDKN2A.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Isotype: IgG Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-HARIDAAEGPSDIPD, from human CDKN2A, at C-terminal (NP_000068.1, NP_001182061.1). Specificity: Recognizes human CDKN2A. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Mawrin C, Kirches E, Schneider-Stock R, Boltze C, Vorwerk CK, von Mawrin A, Kirches E, Schneider-Stock R, Boltze C, Vorwerk CK, von Mawrin A, Kirches E, Schneider-Stock R, Boltze C, Vorwerk CK, von Mawrin A, Kirches E, Schneider-Stock R, Boltze C, Vorwerk Alterations of cell cycle regulators in gliomatosis cerebri. J Neurooncol. 2005 Apr;72(2):115-22.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/10/C8471-65R_1.jpg