Collectrin (TMEM27, Transmembrane protein 27 Collectrin Precursor, NX17, UNQ679, PRO1312) (Biotin)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Collectrin (TMEM27, Transmembrane protein 27 Collectrin Precursor, NX17, UNQ679, PRO1312) (Biotin)

catalog :

C7553

quantity :

50 ug

clonality :

polyclonal

host :

domestic sheep

conjugate :

biotin

reactivity :

mouse

product information

Catalog Number :

C7553

Product wo Prefix :

Collectrin (TMEM27, Transmembrane protein 27 Collectrin Precursor, NX17, UNQ679, PRO1312) (Biotin)

Host :

sheep

Product Type :

Pab

Conjugate :

Biotin

Category :

Antibodies

Size1 :

50 ug

Isotype :

IgG

Desc1 :

Collectrin (also Transmembrane protein 27) is a 37-43kD member of the MEM27 family of proteins. It is expressed on pancreatic beta-cells where it regulates insulin secretion, and on renal tubular epithelium where it mediates amino acid transport. Mature mouse Collectrin is a 208aa type I transmembrane glycoptotein. It contains a 127aa extracellular region (aa15-141) and a 60aa cytoplasmic domain (aa163-222). Collectrin dimerizes on the cell surface, and undergoes proteolytic cleavage to generate a 26kD soluble fragment. Over aa15-144, mouse Collectrin shares 92% and 86% aa identity with rat and human Collectrin, respectively. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 0.1ug/ml. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Immunogen :

Recombinant protein corresponding to Glu15-Ile144 of mouse Collectrin extracellular domain, expressed in NSO cells (Q9ESG4). Species Sequence Homology: rat; 92%, human; 86%

Specificity :

Recognizes the extracellular domain of mouse Collectrin. Species Crossreactivity: recombinant human Collectrin, ~40% .

Purity :

Purified by Immunoaffinity chromatography

Form :

Supplied as lyophilized powder from PBS, 7.4, 50ug BSA per 1ug antibody. Labeled with Biotin. Reconstitute with 250ul sterile PBS.

Concentration :

~0.2mg/ml (after reconstitution)

Desc2 :

Product Type: Pab Isotype: IgG Host: sheep Source: mouse Concentration: ~0.2mg/ml (after reconstitution) Form: Supplied as lyophilized powder from PBS, 7.4, 50ug BSA per 1ug antibody. Labeled with Biotin. Reconstitute with 250ul sterile PBS. Purity: Purified by Immunoaffinity chromatography Immunogen: Recombinant protein corresponding to Glu15-Ile144 of mouse Collectrin extracellular domain, expressed in NSO cells (Q9ESG4). Species Sequence Homology: rat; 92%, human; 86% Specificity: Recognizes the extracellular domain of mouse Collectrin. Species Crossreactivity: recombinant human Collectrin, ~40% . Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

Storage Temperature :

-20°C