Cholecystokinin A Receptor (Cholecystokinin Receptor Type A, CCK-A Receptor, CCKAR, CCK-AR, CCKRA, Cholecystokinin-1 Receptor, CCK1-R) | US Biological C5042-20L product information

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product summary

company name :

US Biological

product type :

antibody

product name :

Cholecystokinin A Receptor (Cholecystokinin Receptor Type A, CCK-A Receptor, CCKAR, CCK-AR, CCKRA, Cholecystokinin-1 Receptor, CCK1-R)

catalog :

C5042-20L

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

product information

Catalog Number :

C5042-20L

Product wo Prefix :

Cholecystokinin A Receptor (Cholecystokinin Receptor Type A, CCK-A Receptor, CCKAR, CCK-AR, CCKRA, Cholecystokinin-1 Receptor, CCK1-R)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

Cholecystokinin A receptor, a Cholecystokinin Receptor, binds sulfated CCK, particularly CCK8. The CCKA receptor mediates gallbladder contraction, gastric emptying, relaxation of the sphincter of Oddi, and insulin secretion. It is also inolved in pancreatic growth, enzyme secretion, and tumorigenesis. Cholecystokinin A receptor has been reported in brain, colon, gall bladder, gastrointestinal tract, kidney, pancreas, small intestine, spinal cord, and stomach. ESTs have been isolated from mouse kidney and heart libraries. Applications: Suitable for use in ELISA, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:4000 Immunohistochemistry (Paraffin): 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Rt

Immunogen :

Synthetic peptide corresponding to C-FEASQKKSAKERKPST, from CCKAR, at the internal region of the protein (NP_000721.1).

Specificity :

Recognizes human CCKAR. Species Crossreactivity: Rat.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-FEASQKKSAKERKPST, from CCKAR, at the internal region of the protein (NP_000721.1). Specificity: Recognizes human CCKAR. Species Crossreactivity: Rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IC IHC

Storage Temperature :

-20°C

Reference :

1. El-Kouhen K, Morisset J. Control of somatostatin (SS) secretion by CCK-1 and CCK-2 receptors' occupation in RIN-14B cells, a rat pancreatic islet cell line. Pancreas. 2010 Mar;39(2):127-34.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/13/C5042-20L_1.jpg