CD48 (FITC) | US Biological C2403-09F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

CD48 (FITC)

catalog :

C2403-09F

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

3H1461 (MEM-102)

reactivity :

human

product information

Catalog Number :

C2403-09F

Product wo Prefix :

CD48 (FITC)

Host :

mouse

Product Type :

Mab

Conjugate :

FITC

Category :

Antibodies

Size1 :

100 ug

Clone # USB :

3H1461 (MEM-102)

Isotype :

IgG1

Desc1 :

CD48 (Blast-1) belongs to the CD2 subset of the Ig superfamily, which includes CD2, CD2F-10, CD58, CD84, CD150, CD229, CD244 and others. These molecules bind to the same or another members of their family, thus mediate homotypic or heterotypic adhesion. CD48 is a GPI-anchored protein broadly expressed on hematopoietic cells and serves as a high affinity ligand for 2B4 and low affinity ligand for CD2. 2B4-CD48 interaction among NK cells and NK-T cells regulates cell proliferation. Signaling through CD48 results in eosinophil activation and CD48 expression is increased in several infectious diseases. Applications: Suitable for use in Flow Cytometry. Other applications have not been tested. Recommended Dilutions: Flow Cytometry: Neat; Use 10ul to label 1x10e6 cells in 100ul. Optimal working dilutions to be determined by researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mk

Immunogen :

Burkitt’s lymphoma cell line Raji

Specificity :

Recognizes the human CD48 antigen which is widely distributed on leucocytes with a distinctive reaction pattern. The antigen is structurally closely related to the B-cell activation antigen Blast-1. Species Crossreactivity: Rhesus monkey

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC).

Concentration :

~0.1mg/ml

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 3H1461 (MEM-102) Host: mouse Source: human Concentration: ~0.1mg/ml Form: Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC). Purity: Purified by Protein A affinity chromatography. Immunogen: Burkitt’s lymphoma cell line Raji Specificity: Recognizes the human CD48 antigen which is widely distributed on leucocytes with a distinctive reaction pattern. The antigen is structurally closely related to the B-cell activation antigen Blast-1. Species Crossreactivity: Rhesus monkey Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

Storage Temperature :

-20°C

Reference :

1. Horejsi, V. et al. (1988). Fol. Biol. (Prague). 34: 23-24. 2. Korinek, V. et al. (1991) Immunogenetics. 33: 108-112. 3. Cinek, T. and Horejsi, V. (1992) J. Immunol. 149: 2262-2270. 4. Staffler, G. et al. (2003) J. Immunol. 171: 1707-1714. 5. Larochelle, A. et al. (2011) Blood. 117:1550-4. 6. Enose-Akahata, Y. et al. (2009) PLoS Pathog. 5: e1000682. 7. Fukushima, K. et al. (2005) J Biol Chem. 280: 18056-62. 8. Kanuga, N. et al. (2002) Invest Ophthalmol Vis Sci. 43: 546-55.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/12/C2403-09F_1.jpg