CAPON (Carboxyl-terminal PDZ Ligand of Neuronal Nitric Oxide Synthase Protein, C-terminal PDZ Ligand of Neuronal Nitric Oxide Synthase Protein, Nitric Oxide Synthase 1 Adaptor Protein, NOS1AP, KIAA0464) | US Biological C1035-39A product information

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product summary

company name :

US Biological

product type :

antibody

product name :

CAPON (Carboxyl-terminal PDZ Ligand of Neuronal Nitric Oxide Synthase Protein, C-terminal PDZ Ligand of Neuronal Nitric Oxide Synthase Protein, Nitric Oxide Synthase 1 Adaptor Protein, NOS1AP, KIAA0464)

catalog :

C1035-39A

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

product information

Catalog Number :

C1035-39A

Product wo Prefix :

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA (Peptide): 1:1000 Immunohistochemistry (Paraffin): 4-6ug/ml Requires steam antigen retrieval with Tris/EDTA buffer pH9.5 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Bo Hu Mo Rt

Immunogen :

Synthetic peptide corresponding to PSKTKYNLVDDGH-C, from the N-terminal of human CAPON,(NP_055512.1, NP_001158229.1). Species sequence homology: bovine, mouse and rat.

Specificity :

Recognizes human CAPON.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Isotype: IgG Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to PSKTKYNLVDDGH-C, from the N-terminal of human CAPON,(NP_055512.1, NP_001158229.1). Species sequence homology: bovine, mouse and rat. Specificity: Recognizes human CAPON. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC

Storage Temperature :

-20°C

Reference :

1. Jaffrey SR, Snowman AM, Eliasson MJ, Cohen NA, Snyder SH. CAPON: a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95. Neuron. 1998 Jan;20(1):115-24.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/46/C1035-39A_1.jpg