antibody

BMP3 (Bone Morphogenetic Protein 3, BMP-3, Bone Morphogenetic Protein 3A, BMP-3A, Osteogenin, BMP3A)

B2553-10D

100 ug

polyclonal

domestic goat

nonconjugated

BMP3 (Bone Morphogenetic Protein 3, BMP-3, Bone Morphogenetic Protein 3A, BMP-3A, Osteogenin, BMP3A)

goat

Pab

Antibodies

100 ug

IgG

The BMPs belong to the TGF-Beta superfamily BMPs stimulate the production of bone matrix proteins and thereby alter stromal cell and osteoclast proliferation, a key step in bone marrow development. In addition to promoting ectopic bone and cartilage development, BMPs regulate the growth, differentiation, chemotaxis, proliferation, and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells, and neuronal cells. BMPs also play a role in dorsal/ventral patterning. BMP3, highly expressed in lung, ovary and small intestine, participates in cartilage and bone formation. BMP3 and BMP2 genes map to conserved regions between human and mouse. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:8000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

Synthetic peptide corresponding to C-GHRNFPTGTV PKWDSH, from BMP3, at the internal region of the protein (NP_001192.2).

Recognizes BMP3. Species sequence homology: Human.

Purified by immunoaffinity chromatography

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

~0.5mg/ml

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-GHRNFPTGTV PKWDSH, from BMP3, at the internal region of the protein (NP_001192.2). Specificity: Recognizes BMP3. Species sequence homology: Human. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E

-20°C

1. Nacamuli RP, Fong KD, Lenton KA, Song HM, Fang TD, Salim A, Longaker MT. Expression and possible mechanisms of regulation of BMP3 in rat cranial sutures. Plast Reconstr Surg. 2005 Oct;116(5):1353-62.