BGN (Biglycan, Bone/Cartilage Proteoglycan I, PG-S1, SLRR1A) | US Biological B1089-42 product information

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product summary

company name :

US Biological

product type :

antibody

product name :

BGN (Biglycan, Bone/Cartilage Proteoglycan I, PG-S1, SLRR1A)

catalog :

B1089-42

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

product information

Catalog Number :

B1089-42

Product wo Prefix :

BGN (Biglycan, Bone/Cartilage Proteoglycan I, PG-S1, SLRR1A)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

BGN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein is thought to function in connective tissue metabolism by binding to collagen fibrils and transfering growth factor-beta. It may promote neuronal survival. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:8000 Western Blot: 0.1-0.3ug/ml, observed in rat skin lysates on ~38-40kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Ca Hu Mo Rt

Immunogen :

Synthetic peptide corresponding to C-DRLAIQFGNYKK, from rat BGN, at C-terminal (NP_001702.1).

Specificity :

Recognizes rat BGN. Species sequence homology: Canine, human and mouse.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Host: goat Source: rat Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-DRLAIQFGNYKK, from rat BGN, at C-terminal (NP_001702.1). Specificity: Recognizes rat BGN. Species sequence homology: Canine, human and mouse. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Chen WB, Lenschow W, Tiede K, Fischer JW, Kalthoff H, Ungefroren H. Smad4/DPC4-dependent regulation of biglycan gene expression by transforming growth factor-beta in pancreatic tumor cells. J Biol Chem. 2002 Sep 27;277(39):36118-28. Epub 2002 Jul 24.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/1/B1089-42_1.jpg