APOBEC2 (Probable C->U-editing Enzyme APOBEC-2) | US Biological A2298-88P product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

APOBEC2 (Probable C->U-editing Enzyme APOBEC-2)

catalog :

A2298-88P

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

product information

Catalog Number :

A2298-88P

Product wo Prefix :

APOBEC2 (Probable C->U-editing Enzyme APOBEC-2)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:128,000 Western Blot: 1-3ug/ml, observed in human skeletal muscle lysates on ~26kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Bo Hu Mo Rt

Immunogen :

Synthetic peptide corresponding to C-KPQDFEYVWQN, from human APOBEC2, at the internal region of the protein (NP_006780.1).

Specificity :

Recognizes human APOBEC2. Species sequence homology: Bovine, mouse and rat.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-KPQDFEYVWQN, from human APOBEC2, at the internal region of the protein (NP_006780.1). Specificity: Recognizes human APOBEC2. Species sequence homology: Bovine, mouse and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Prochnow C, Bransteitter R, Klein MG, Goodman MF, Chen XS. The APOBEC-2 crystal structure and functional implications for the deaminase AID. Nature. 2007 Jan 25;445(7126):447-51. Epub 2006 Dec 24.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/3/A2298-88P_1.jpg