a1-Antichymotrypsin (AACT, Alpha1-ACT, Alpha-1-antichymotrypsin, ACT, Cell Growth-inhibiting Gene 24/25 Protein, Serpin A3, SERPINA3, GIG24, GIG25) | US Biological A2298-01U product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

a1-Antichymotrypsin (AACT, Alpha1-ACT, Alpha-1-antichymotrypsin, ACT, Cell Growth-inhibiting Gene 24/25 Protein, Serpin A3, SERPINA3, GIG24, GIG25)

catalog :

A2298-01U

quantity :

500 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

A2298-01U

Product wo Prefix :

a1-Antichymotrypsin (AACT, Alpha1-ACT, Alpha-1-antichymotrypsin, ACT, Cell Growth-inhibiting Gene 24/25 Protein, Serpin A3, SERPINA3, GIG24, GIG25)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

500 ul

Isotype :

IgG

Desc1 :

Alpha 1 ACT is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1- ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Frozen/Paraffin): 1:25-1:50 for 30-60 minutes at RT. Stains monocytes and macrophages in human tissues and does not stain any other cell type. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Immunogen :

Alpha-1-antichymotrypsin isolated from human serum. Cellular Localization: Cytoplasmic. Species Sequence Homology: All Mammals

Specificity :

Recognizes human Alpha-1-antichymotrypsin.

Purity :

Purified by affinity chromatography

Form :

Supplied as a liquid in PBS, 0.09% sodium azide

Concentration :

Not Determined

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: Not Determined Form: Supplied as a liquid in PBS, 0.09% sodium azide Purity: Purified by affinity chromatography Immunogen: Alpha-1-antichymotrypsin isolated from human serum. Cellular Localization: Cytoplasmic. Species Sequence Homology: All Mammals Specificity: Recognizes human Alpha-1-antichymotrypsin. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

IHC

Storage Temperature :

4°C Do not freeze

Reference :

1. Meis et al. Am J Clin Pathol 86: 591, 1986. 2. Nathrath et al. Acta Histochem 25: 69, 1982.