antibody

ADH7 (Alcohol Dehydrogenase Class 4 mu/sigma Chain, Alcohol Dehydrogenase Class IV mu/sigma Chain, Gastric Alcohol Dehydrogenase, Retinol Dehydrogenase)

A1331-07C

100 ug

polyclonal

domestic goat

nonconjugated

ADH7 (Alcohol Dehydrogenase Class 4 mu/sigma Chain, Alcohol Dehydrogenase Class IV mu/sigma Chain, Gastric Alcohol Dehydrogenase, Retinol Dehydrogenase)

goat

Pab

Antibodies

100 ug

IgG

This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu Mo

Synthetic peptide corresponding to CISPKDSTKPISE, from ADH7, at the internal region of the protein (NP_000664.2).

Recognizes ADH7. Species sequence homology: Human and mouse.

Purified by immunoaffinity chromatography

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

~0.5mg/ml

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to CISPKDSTKPISE, from ADH7, at the internal region of the protein (NP_000664.2). Specificity: Recognizes ADH7. Species sequence homology: Human and mouse. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E

-20°C

1. Zgombic-Knight M, Foglio MH, Duester G. Genomic structure and expression of the ADH7 gene encoding human class IV alcohol dehydrogenase, the form most efficient for retinol metabolism in vitro. J Biol Chem. 1995 Mar 3;270(9):4305-11.