AKT2 (v-akt murine thymoma viral oncogene homolog 2, PKBB, PKBBETA, PKB beta, PRKBB, Protein kinase Akt-2, Protein kinase B beta, RAC-BETA, RAC-beta serine/threonine-protein kinase, RAC-PK-beta) | US Biological A1125-25T product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

AKT2 (v-akt murine thymoma viral oncogene homolog 2, PKBB, PKBBETA, PKB beta, PRKBB, Protein kinase Akt-2, Protein kinase B beta, RAC-BETA, RAC-beta serine/threonine-protein kinase, RAC-PK-beta)

catalog :

A1125-25T

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10F597

reactivity :

human

product information

Catalog Number :

A1125-25T

Product wo Prefix :

AKT2 (v-akt murine thymoma viral oncogene homolog 2, PKBB, PKBBETA, PKB beta, PRKBB, Protein kinase Akt-2, Protein kinase B beta, RAC-BETA, RAC-beta serine/threonine-protein kinase, RAC-PK-beta)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

10F597

Isotype :

IgG2b

Desc1 :

Akt2 (also designated protein kinase B beta or v-akt murine thymoma viral oncogene homolog 2 ), with 481-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt3. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. Among the members of AKT family, Akt2 is associated with the development of human cancers. Akt2 inhibits cisplatin-induced JNK/p38 and Bax activation through phosphorylation of ASK1 and thus, plays an important role in chemoresistance. Further, Akt2 plays a specific role in muscle differentiation. Applications: Suitable for use in ELISA, Western Blot and Immunofluorescence. Other applications not tested. Recommended Dilution: ELISA: 1:10,000 Western Blot: 1:500-1:2000 Immunofluorescence: 1:200-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mk Rt

Immunogen :

Purified recombinant fragment of human AKT2 expressed in E. coli.

Specificity :

Recognizes human AKT2 at 60kD. Species Crossreactivity: rat, monkey.

Purity :

Ascites

Form :

Supplied as liquid, 0.04% sodium azide.

Concentration :

Not determined

Desc2 :

Product Type: Mab Isotype: IgG2b Clone No: 10F597 Host: mouse Source: human Concentration: Not determined Form: Supplied as liquid, 0.04% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of human AKT2 expressed in E. coli. Specificity: Recognizes human AKT2 at 60kD. Species Crossreactivity: rat, monkey. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IF WB

Storage Temperature :

-20°C

Reference :

1. Am J Physiol Endocrinol Metab. 2004 Jul; 287(1):E8-E15, 2. Oncol Rep. 2004 Jan;11(1):25-32, 3. Cancer Res. 2003 Jan 1; 63(1):196-206.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/25/A1125-25T_1.jpg