Actin, alpha, Smooth Muscle (PE) | US Biological A0760-27F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Actin, alpha, Smooth Muscle (PE)

catalog :

A0760-27F

quantity :

100Tests

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

9H15

The same clone is also sold as:

MyBioSource: MBS633258

reactivity :

human, mouse, rat

product information

Catalog Number :

A0760-27F

Product wo Prefix :

Actin, alpha, Smooth Muscle (PE)

Host :

mouse

Product Type :

Mab

Conjugate :

Category :

Antibodies

Size1 :

100Tests

Clone # USB :

9H15

Isotype :

IgG2a

Desc1 :

Actins are highly conserved proteins expressed in all eukaryotic cells. Actin filaments form part of the cytoskeleton and play essential roles in regulating cell shape and movement. Six distinct actin isotypes have been identified in mammalian cells. Each is encoded by a separated gene and is expressed in a developmentally regulated and tissue-specific manner, alpha and beta cytoplasmic actins are expressed in a wide variety of cells; whereas, expression of alpha skeletal, alpha cardiac, alpha vascular, and gamma enteric actins are more restricted to specialized muscle cell type. Smooth muscle alpha actin is of further interest because it is one of a few genes whose expression is relatively restricted to vascular smooth muscle cells. Further more, expression of smooth muscle alpha actin is regulated by hormones, cell proliferation, and altered by pathological conditions including oncogenic transformation and atherosclerosis. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry (Intercellular): Neat. 10ul labels up to 1x10e6 cells. Optimal dilutions to be determined by the researcher. Hybridoma: Fusion of a mouse myeloma with B cells obtained from a rat immunized with a synthetic decapeptide from the N-terminal of Alpha-Smooth Muscle Actin. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Calc Crossreactivity :

Hu Mo Rb Rt

Immunogen :

Synthetic decapeptide corresponding to the N-terminal residues of human Alpha-Smooth Muscle Actin.

Specificity :

Recognizes human Alpha-Smooth Muscle Actin. Species Crossreactivity: rabbit, mouse and rat

Purity :

Purified by Protein A affinity chromatography from hybridoma culture supernatant.

Form :

Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).

Concentration :

As Reported

Desc2 :

Product Type: Mab Isotype: IgG2a Clone No: 9H15 Host: mouse Source: human Concentration: As Reported Form: Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE). Purity: Purified by Protein A affinity chromatography from hybridoma culture supernatant. Immunogen: Synthetic decapeptide corresponding to the N-terminal residues of human Alpha-Smooth Muscle Actin. Specificity: Recognizes human Alpha-Smooth Muscle Actin. Species Crossreactivity: rabbit, mouse and rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

Storage Temperature :

4°C Do not freeze

Reference :

1. Skalli, O., et al., J. Cell Biol. 103: 2787 (1986). 2. Oishi, K., et al., J. Physiol. 540: 139 (2002).

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/22/A0760-27F_1.jpg