ABCE1 (ATP-binding Cassette Sub-family E Member 1, 2'-5'-oligoadenylate-binding Protein, HuHP68, RNase L Inhibitor, Ribonuclease 4 Inhibitor, RNS4I, RLI, RNASEL1, RNASELI, RNS4I, OK/SW-cl.40) | US Biological A0004-03E product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

ABCE1 (ATP-binding Cassette Sub-family E Member 1, 2'-5'-oligoadenylate-binding Protein, HuHP68, RNase L Inhibitor, Ribonuclease 4 Inhibitor, RNS4I, RLI, RNASEL1, RNASELI, RNS4I, OK/SW-cl.40)

catalog :

A0004-03E

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

product information

Catalog Number :

A0004-03E

Product wo Prefix :

ABCE1 (ATP-binding Cassette Sub-family E Member 1, 2'-5'-oligoadenylate-binding Protein, HuHP68, RNase L Inhibitor, Ribonuclease 4 Inhibitor, RNS4I, RLI, RNASEL1, RNASELI, RNS4I, OK/SW-cl.40)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Bo Ca Hu Mo Rt

Immunogen :

Synthetic peptide corresponding to NHDKCKPKKCRQEC, from ABCE1, at N-terminal (NP_002931.2, NP_001035809.1).

Specificity :

Recognizes ABCE1. Species sequence homology: Bovine, human, mouse, canine and rat.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to NHDKCKPKKCRQEC, from ABCE1, at N-terminal (NP_002931.2, NP_001035809.1). Specificity: Recognizes ABCE1. Species sequence homology: Bovine, human, mouse, canine and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

Storage Temperature :

-20°C

Reference :

1. Shichijo S, Ishihara Y, Azuma K, Komatsu N, Higashimoto N, Ito M, Nakamura T, Ueno T, Harada M, Itoh K. ABCE1, a member of ATP-binding cassette transporter gene, encodes peptides capable of inducing HLA-A2-restricted and tumor-reactive cytotoxic T lymphocytes in colon cancer patients. Oncol Rep. 2005 May;13(5):907-13.