This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
Mucin 2 (MUC2, Mucin-2)
catalog :
138573
quantity :
20 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CCP58
The same clone is also sold as:
The same clone is also sold as:
- Novus Biologicals: NBP2-25221
- BD Biosciences: 555926
- OriGene: AM33118PU-T, AM33118PU-S
- Santa Cruz Biotechnology: sc-7314
- Dako: M7313
- Abnova: MAB11323
reactivity :
human
product information
Catalog Number :
138573
Product wo Prefix :
Mucin 2 (MUC2, Mucin-2)
Host :
mouse
Product Type :
Mab
Category :
Antibodies
Size1 :
20 ug
Clone # USB :
CCP58
Isotype :
IgG1,k
Desc1 :
Recognizes a single glycoprotein of 520kD, identified as mucin 2 (MUC2). This monoclonal antibody shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.
Applications:
Suitable for use in ELISA, Flow Cytometry, Western Blot, Immunoprecipitation, Immunofluorescence and Immunohistochemistry. Other applications not tested.
Recommended Dilution:
Flow Cytometry: 0.5-1ug/10e6 cells
Western Blot: 0.5-1ug/ml
Immunofluorescence: 1-2ug/ml
Immunoprecipitation: 1-2ug/500ug protein lysate
Immunohistochemistry (Frozen & Formalin fixed paraffin embedded): 0.5-1ug/ml/30min @ RT
Optimal dilutions to be determined by the researcher.
Positive Control:
LS174T cells or small intestine
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
Immunogen :
Synthetic peptide corresponding to 29aa, KYPTTTPISTTTMVTPTPTPTGTQTPTTT, from MUC2, coupled to KLH.
Specificity :
Recognizes human MUC2.
Purity :
Purified by Protein G affinity chromatography.
Form :
Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. Also available without BSA and azide, see 138573-AF.
Concentration :
~0.2mg/ml
Desc2 :
Product Type: Mab
Isotype: IgG1,k
Clone No: CCP58
Host: mouse
Source: human
Concentration: ~0.2mg/ml
Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. Also available without BSA and azide, see 138573AF.
Purity: Purified by Protein G affinity chromatography.
Immunogen: Synthetic peptide corresponding to 29aa, KYPTTTPISTTTMVTPTPTPTGTQTPTTT, from MUC2, coupled to KLH.
Specificity: Recognizes human MUC2.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E FC IF IHC IP WB
Storage Temperature :
-20°C
Reference :
1. Xing PX, et. al. Journal of the National Cancer Institute, 1992, 84(9):699-703.
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/12/138573_1jpeg
company information
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
service@usbio.net
https://www.usbio.net800-520-3011
headquarters: USA
United States Biological is a primary brand for the Life Science Industry. We are committed to reducing the cost of research with value, integrity and a truly personal buying experience.
questions and comments