This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
MUC5AC (Apomucin Major Airway GlycoProtein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin, TBM, Mucin 5AC, Gastric Mucin)
catalog :
138572
quantity :
20 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
45M1

The same clone is also sold as:
reactivity :
human
product information
Catalog Number :
138572
Product wo Prefix :
MUC5AC (Apomucin Major Airway GlycoProtein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin, TBM, Mucin 5AC, Gastric Mucin)
Host :
mouse
Product Type :
Mab
Category :
Antibodies
Size1 :
20 ug
Clone # USB :
45M1
Isotype :
IgG1,k
Desc1 :
This monoclonal antibody recognizes the peptide core of gastric mucin M1 (>1,000kD) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epi thelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not w ith normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin r eactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fet al colonic) mucins. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30min at RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10mM citrate buffer, pH 6, for 10-20mins followed by coooling at RT for 20mins. Optimal dilutions to be determined by the researcher. Positive Control: Stomach Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Ch Fe Hu Mk Mo Po Rb Rt
Immunogen :
M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient
Specificity :
Recognizes human MUC5AC. Species Crossreactivity: feline, chicken, hedgehog, monkey, mouse, porcine, rabbit, rat. Does not react with bovine.
Purity :
Purified by Protein G affinity chromatography.
Form :
Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. Also available without BSA and azide, see 138572-AF.
Concentration :
~0.2mg/ml
Desc2 :
Product Type: Mab Isotype: IgG1,k Clone No: 45M1 Host: mouse Source: human Concentration: ~0.2mg/ml Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. Also available without BSA and azide, see 138572-AF. Purity: Purified by Protein G affinity chromatography. Immunogen: M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient Specificity: Recognizes human MUC5AC. Species Crossreactivity: feline, chicken, hedgehog, monkey, mouse, porcine, rabbit, rat. Does not react with bovine. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E IHC
Storage Temperature :
-20°C
Reference :
1. Bara J et. al. International Journal of Cancer, 1991, 47(2):304-10. 2. Bara J et. al. Journal of Immunological Methods, 1992, 149(1):105-13.
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/6/138572_1.jpg
Picture4 Text :
Immunohistochemistry analysis of formalin-fixed, paraffin-embedded human Stomach using 138572.
company information
US Biological
4 Technology Way
Salem, MA01970
service@usbio.net
https://www.usbio.net
800-520-3011
headquarters: USA
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