MALT1 (Paracaspase, Mucosa-associated Lymphoid Tissue Lymphoma Translocation Protein 1)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

MALT1 (Paracaspase, Mucosa-associated Lymphoid Tissue Lymphoma Translocation Protein 1)

catalog :

138567

quantity :

20 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MT1/410

The same clone is also sold as:

Abnova: MAB11232
Abcam: ab212285, ab178581
Novus Biologicals: NBP2-29430, NBP2-33054

reactivity :

human

product information

Catalog Number :

138567

Product wo Prefix :

MALT1 (Paracaspase, Mucosa-associated Lymphoid Tissue Lymphoma Translocation Protein 1)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

20 ug

Clone # USB :

MT1/410

Isotype :

IgG1,k

Desc1 :

Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells. Applications: Suitable for use in Western Blot, Flow Cytometry, Immunofluorescence and Immunohistochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: 0.5-1ug/10e6 cells Immunofluorescence: 1-2ug/ml Western Blot: 0.5-1ug/ml Immunohistochemistry (Formalin-fixed): 0.5-1ug/ml for 30min at RT Requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 minutes Optimal dilutions to be determined by the researcher. Positive Control: Jurkat, Daudi or HeLa cells. Tonsil or lymphoma. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Recombinant protein corresponding to aa701-808 from human MALT1.

Specificity :

Recognizes human MALT1.

Purity :

Purified by Protein A/G affinity chromatography.

Form :

Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. Also available without BSA and azide, see 138567-AF.

Concentration :

~0.2mg/ml

Desc2 :

Product Type: Mab Isotype: IgG1,k Clone No: MT1/410 Host: mouse Source: human Concentration: ~0.2mg/ml Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. Also available without BSA and azide, see 138567-AF. Purity: Purified by Protein A/G affinity chromatography. Immunogen: Recombinant protein corresponding to aa701-808 from human MALT1. Specificity: Recognizes human MALT1. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FC IF IHC WB

Storage Temperature :

-20°C

Reference :

1. Ye H et. al. J Pathol 2005; 205 : 293-301.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/31/138567_1.jpg