This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
ERBB2 (HER-2, CD340)
catalog :
138547
quantity :
20 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HRB2/451

The same clone is also sold as:
reactivity :
human
product information
Catalog Number :
138547
Product wo Prefix :
ERBB2 (HER-2, CD340)
Host :
mouse
Product Type :
Mab
Category :
Antibodies
Size1 :
20 ug
Clone # USB :
HRB2/451
Isotype :
IgG1,k
Desc1 :
This monoclonal antibody is specific to c-erb B-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erb B-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary. Applications: Suitable for use in Flow Cytometry and Immunofluorescence. Other applications not tested. Recommended Dilutions: Flow Cytometry: 1.2ug/10e6 cells Immunofluorescence: 1-4ug/ml Optimal dilutions to be determined by the researcher. Positive Control: MCF-7, SKBR-3 Cells or Breast Cancers Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
Immunogen :
Recombinant protein corresponding to human HER-2. Cellular Localization: Cell Surface
Specificity :
Recognizes human HER-2.
Purity :
Purified by Protein A/G affinity chromatography.
Form :
Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. Also available without BSA and azide, see 138547-AF.
Concentration :
~0.2mg/ml
Desc2 :
Product Type: Mab Isotype: IgG1,k Clone No: HRB2/451 Host: mouse Source: human Concentration: ~0.2mg/ml Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. Also available without BSA and azide, see 138547-AF. Purity: Purified by Protein A/G affinity chromatography. Immunogen: Recombinant protein corresponding to human HER-2. Cellular Localization: Cell Surface Specificity: Recognizes human HER-2. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
FC IF
Storage Temperature :
-20°C
Reference :
1. Utrilla JC, et al. Histopathology. 34: 60-65 (1999). 2. Wright C, et al. British Journal of Cancer. 65: 118-121 (1992). 3. Corbett IP, et al. Journal of Pathology. 161:15-25 (1990).
company information
US Biological
4 Technology Way
Salem, MA01970
service@usbio.net
https://www.usbio.net
800-520-3011
headquarters: USA
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