CD5 (T-cell Surface Glycoprotein CD5) discontinued | US Biological 138520 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

CD5 (T-cell Surface Glycoprotein CD5) discontinued

catalog :

138520

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

C5/473

The same clone is also sold as:

OriGene: AM32836PU-T, AM32836PU-S
Abnova: MAB11244

reactivity :

human

product information

Catalog Number :

138520

Product wo Prefix :

CD5 (T-cell Surface Glycoprotein CD5) discontinued

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

C5/473

Isotype :

IgG1,k

Desc1 :

CD5, a 67kD Type I transmembrane glycoprotein, is a member of SRCR superfamily expressed specifically of thymocytes, mature T-cells and B-1a cells. CD5 has an extracellular domain with 3 SRCR domains and cytoplasmic tail is devoid of any intrinsic enzyme activity. CD5 functions as a dual receptor modulating either positive or negative co-stimulatory signals depending on the cell type and the developmental stage. It binds CD72 and provides co-stimulatory signal for T-cell growth. CD5 plays an important role in thymocyte development and also fine-tunes TCR signaling. It is associated with antigen-specific receptor complex expressed on T-cells and B-1a cells and regulates T and B-cell mediated responses. CD5 signaling involves various kinases including PI3K, Src family tyrosine kinases, CKII, Ras GAP, and members of MAPK. Applications: Suitable for use in Flow Cytometry, Immunofluorescence, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: 5-10ul/10e6 cells Immunofluorescence: 1:50-1:100 Western Blot: 1:100-1:200 Immunoprecipitation: 5-10ul/500ug protein lysate Immunohistochemistry (Frozen & Formalin fixed paraffin embedded): 1:100-1:200/30min @ RT Optimal dilutions to be determined by the researcher. Positive Control: 293T, Ramos, or MOLT-4 Cells. Tonsil Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Recombinant protein fragment corresponding to human CD5.

Specificity :

Recognizes human CD5.

Purity :

Supernatant

Form :

Supplied as a liquid in 0.05% sodium azide.

Concentration :

Not determined

Desc2 :

Product Type: Mab Isotype: IgG1,k Clone No: C5/473 Host: mouse Source: human Concentration: Not determined Form: Supplied as a liquid in 0.05% sodium azide. Purity: Supernatant Immunogen: Recombinant protein fragment corresponding to human CD5. Specificity: Recognizes human CD5. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FC IF IHC IP WB

Storage Temperature :

-20°C

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/19/138520_1.jpg