This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
CD45RB (CD45 Antigen, B220, GP180, Leukocyte Common Antigen, LCA, L-CA, LY5, LY-5, Protein Tyrosine Phosphatase Receptor Type C Polypeptide, PTPRC, T200, T200 Glycoprotein) discontinued
catalog :
138518
quantity :
100 ul
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PD7/26
The same clone is also sold as:
The same clone is also sold as:
- Santa Cruz Biotechnology: sc-53203
- Invitrogen: MA5-12496, 50-9458-82, 14-9458-37, 14-9458-82, 53-9458-82
- Abnova: MAB11484
- OriGene: AM32859PU-T, AM32859PU-S
- Novus Biologicals: NBP2-32937-0.1mg, NBP2-34708-0.1mg
reactivity :
human
product information
Catalog Number :
138518
Product wo Prefix :
CD45RB (CD45 Antigen, B220, GP180, Leukocyte Common Antigen, LCA, L-CA, LY5, LY-5, Protein Tyrosine Phosphatase Receptor Type C Polypeptide, PTPRC, T200, T200 Glycoprotein) discontinued
Host :
mouse
Product Type :
Mab
Category :
Antibodies
Size1 :
100 ul
Clone # USB :
PD7/26
Isotype :
IgG1,k
Desc1 :
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
Applications:
Suitable for use in Immunofluorescence, Flow Cytometry, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended Dilution:
Immunofluorescence: 1:50-1:100
Flow Cytometry: 5-10ul/10e6 cells
Western Blot: 1:100-1:200
Immunohistochemistry (Frozen, Formalin fixed paraffin embedded): 1:100-1:200/30min @ RT
Immunoprecipitation: 5-10ul/500ug protein lysate
Optimal dilutions to be determined by the researcher.
Positive Control:
Ramos, U-698, or GA-10 cells. Tonsil
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
Immunogen :
Human peripheral blood lymphocytes maintained in T-cell growth factor.
Specificity :
Recognizes human CD45RB.
Purity :
Supernatant
Form :
Supplied as a liquid, 0.05% sodium azide.
Concentration :
Not determined
Desc2 :
Product Type: Mab
Isotype: IgG1,k
Clone No: PD7/26
Host: mouse
Source: human
Concentration: As reported
Form: Supplied as a liquid, 0.05% sodium azide.
Purity: Supernatant
Immunogen: Human peripheral blood lymphocytes maintained in T-cell growth factor.
Specificity: Recognizes human CD45RB.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
FC IF IHC IP WB
Storage Temperature :
-20°C
Reference :
1. Gatter KC et. al. Lancet, 1985 Jun 8, 1(8441):1302-5. 2. Michie SA et. al. American Journal of Clinical Pathology, 1987, 88(4) 457-62.
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/12/138518_1jpeg
company information
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
service@usbio.net
https://www.usbio.net800-520-3011
headquarters: USA
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