This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
CD45 (CD45 Antigen, B220, GP180, Leukocyte Common Antigen, LCA, L-CA, LY5, LY-5, Protein Tyrosine Phosphatase Receptor Type C, Protein Tyrosine Phosphatase Receptor Type C Polypeptide, PTPRC, T200, T200 Glycoprotein) discontinued
catalog :
138516
quantity :
100 ul
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2B11

The same clone is also sold as:
reactivity :
human
product information
Catalog Number :
138516
Product wo Prefix :
CD45 (CD45 Antigen, B220, GP180, Leukocyte Common Antigen, LCA, L-CA, LY5, LY-5, Protein Tyrosine Phosphatase Receptor Type C, Protein Tyrosine Phosphatase Receptor Type C Polypeptide, PTPRC, T200, T200 Glycoprotein) discontinued
URL USB :
www.usbio.net/antibodies/138516/CD45-CD45-Antigen-B220-GP180-Leukocyte-Common-Antigen-LCA-LCA-LY5-LY5-Protein-Tyrosine-Phosphatase-Receptor-Type-C-Protein-Tyrosine-Phosphatase-Receptor-Type-C-Polypeptide-PTPRC-T200-T200-Glycoprotein-discontinued
Host :
mouse
Product Type :
Mab
Category :
Antibodies
Size1 :
100 ul
Clone # USB :
2B11
Isotype :
IgG1,k
Desc1 :
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms. Applications:. Suitable for use in Immunofluorescence, Flow Cytometry, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution:. Immunofluorescence: 1:50-1:100. Flow Cytometry: 5-10ul/10e6 cells. Western Blot: 1:100-1:200. Immunohistochemistry (Frozen, Formalin fixed paraffin embedded): 1:100-1:200/30min @ RT. Immunoprecipitation: 5-10ul/500ug protein lysate. Optimal dilutions to be determined by the researcher. Positive Control:. Ramos, U-698, or GA-10 cells. Tonsil. Storage and Stability:. May be stored at 4 C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
Immunogen :
Isolated neoplastic cells from T cell lymphoma
Specificity :
Recognizes human CD45.
Purity :
Supernatant
Form :
Supplied as a liquid, 0.05% sodium azide.
Concentration :
Not determined
Desc2 :
Product Type: Mab. Isotype: IgG1,k. Clone No: 2B11. Host: mouse. Source: human. Concentration: Not determined. Form: Supplied as a liquid, 0.05% sodium azide. Purity: Supernatant. Immunogen: Isolated neoplastic cells from T cell lymphoma. Specificity: Recognizes human CD45. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
FC IF IHC IP WB
Storage Temperature :
-20 C
Reference :
1. Gatter KC et. al. Lancet, 1985 Jun 8, 1(8441):1302-5. 2. Michie SA et. al. American Journal of Clinical Pathology, 1987, 88(4):457-62.
Picture 1 File Name :
usbio-images.r.worldssl.net/prodimages/0/138516_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
service@usbio.net
https://www.usbio.net
800-520-3011
headquarters: USA
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