CD30 (CD30L receptor, Cytokine receptor CD30, Ki-1 antigen, Lymphocyte activation antigen CD30, Tumor necrosis factor receptor superfamily member 8 (TNFRSF8))

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

CD30 (CD30L receptor, Cytokine receptor CD30, Ki-1 antigen, Lymphocyte activation antigen CD30, Tumor necrosis factor receptor superfamily member 8 (TNFRSF8))

catalog :

138508

quantity :

20 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CD30/412

The same clone is also sold as:

Abnova: MAB11230
Abcam: ab187367, ab213047

reactivity :

human

product information

Catalog Number :

138508

Product wo Prefix :

CD30 (CD30L receptor, Cytokine receptor CD30, Ki-1 antigen, Lymphocyte activation antigen CD30, Tumor necrosis factor receptor superfamily member 8 (TNFRSF8))

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

20 ug

Clone # USB :

CD30/412

Isotype :

IgG2b,k

Desc1 :

CD30 is synthesized as a 90kD precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kD glycoprotein. In Hodgkin's disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This monoclonal antibody distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45). Applications: Suitable for use in ELISA, Flow Cytometry, Immunofluorescence and Immunohistochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: 0.5-1ug/10e6 cells Immunofluorescence: 1-2ug/ml Immunohistochemistry (Frozen & Formalin fixed paraffin embedded): 0.5-1ug/ml/30min @ RT Optimal dilutions to be determined by the researcher. Positive Control: Hodgkin’s lymphoma Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Recombinant protein corresponding to human CD30.

Specificity :

Recognizes human CD30. Recognizes a single chain glycoprotein of 105/120kD, identified as CD30/Ki-1.

Purity :

Purified by Protein A/G affinity chromatography.

Form :

Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. Also available without BSA and azide, see 138508-AF.

Concentration :

~0.2mg/ml

Desc2 :

Product Type: Mab Isotype: IgG2b,k Clone No: CD30/412 Host: mouse Source: human Concentration: ~0.2mg/ml Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. Also available without BSA and azide, see 138508AF. Purity: Purified by Protein A/G affinity chromatography. Immunogen: Recombinant protein corresponding to human CD30. Specificity: Recognizes human CD30. Recognizes a single chain glycoprotein of 105/120kD, identified as CD30/Ki-1. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E FC IF IHC

Storage Temperature :

-20°C

Reference :

1. Schwarting R, et. al. Blood, 1989, 74(5):1678-89.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/7/138508_1.jpg