YBX1, ID (YBX1, NSEP1, YB1, Nuclease-sensitive element-binding protein 1, CCAAT-binding transcription factor I subunit A, DNA-binding protein B, Enhancer factor I subunit A, Y-box transcription factor, Y-box-binding protein 1) (APC) | US Biological 043945-APC product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

YBX1, ID (YBX1, NSEP1, YB1, Nuclease-sensitive element-binding protein 1, CCAAT-binding transcription factor I subunit A, DNA-binding protein B, Enhancer factor I subunit A, Y-box transcription factor, Y-box-binding protein 1) (APC)

catalog :

043945-APC

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

APC

reactivity :

human

product information

Catalog Number :

043945-APC

Product wo Prefix :

URL USB :

www.usbio.net/antibodies/043945-APC/YBX1-ID-YBX1-NSEP1-YB1-Nucleasesensitive-elementbinding-protein-1-CCAATbinding-transcription-factor-I-subunit-A-DNAbinding-protein-B-Enhancer-factor-I-subunit-A-Ybox-transcription-factor-Yboxbinding-protein-1-APC

Host :

rabbit

Product Type :

Pab

Conjugate :

APC

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Regulates the transcription of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Applications:. Suitable for use in Western Blot, Immunofluorescence and FLISA. Other applications have not been tested. Recommended Dilution:. Optimal dilutions to be determined by the researcher. Storage and Stability:. Store product at 4 C in the dark. DO NOT FREEZE! Stable at 4 C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

YBX1, NSEP1, YB1, Nuclease-sensitive element-binding protein 1, CCAAT-binding transcription factor I subunit A, DNA-binding protein B, Enhancer factor I subunit A, Y-box transcription factor, Y-box-binding protein 1

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 149-178 in the central region of human YBX1, UniProt Accession #P67809. Species sequence homology: bovine, mouse, rabbit, rat

Specificity :

Recognizes human YBX1.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Concentration :

As reported

Desc2 :

Product Type: Pab. Isotype: IgG. Host: rabbit. Source: human. Concentration: As reported. Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 149-178 in the central region of human YBX1, UniProt Accession #P67809. Species sequence homology: bovine, mouse, rabbit, rat. Specificity: Recognizes human YBX1. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FL IF WB

Storage Temperature :

4 C Do Not Freeze

Reference :

Yu, Y.N., et al. Int. J. Oncol. 37(2):483-492(2010) Lovett, D.H., et al. Biochem. Biophys. Res. Commun. 398(3):482-488(2010) Takahashi, M., et al. Cancer Sci. 101(6):1367-1373(2010) Cobbold, L.C., et al. Oncogene 29(19):2884-2891(2010) To, K., et al. Cancer Res. 70(7):2840-2851(2010)

Picture 1 File Name :

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