VEGFA, ID (VEGFA, VEGF, Vascular endothelial growth factor A, Vascular permeability factor)

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product summary

company name :

US Biological

product type :

antibody

product name :

VEGFA, ID (VEGFA, VEGF, Vascular endothelial growth factor A, Vascular permeability factor)

catalog :

043741

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

043741

Product wo Prefix :

VEGFA, ID (VEGFA, VEGF, Vascular endothelial growth factor A, Vascular permeability factor)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

VEGFA, VEGF, Vascular endothelial growth factor A, Vascular permeability factor

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 140-168 in the Central region of human VEGFA, UniProt Accession #NP_001020537.

Specificity :

Recognizes human VEGFA.

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 140-168 in the Central region of human VEGFA, UniProt Accession #NP_001020537. Specificity: Recognizes human VEGFA. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Shrivastava-Ranjan, P., et al. J. Virol. 84(21):11227-11234(2010) Kim, Y.H., et al. Gynecol. Oncol. 119(2):232-236(2010) Yang, Y., et al. Exp. Biol. Med. (Maywood) 235(10):1204-1211(2010) Huez, I., et al. Mol. Endocrinol. 15(12):2197-2210(2001) Tee, M.K., et al. Biochem. J. 359 (PT 1), 219-226 (2001) :

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/29/043741_1.jpg