TNFRSF13C, NT (TNFRSF13C, BAFFR, BR3, Tumor necrosis factor receptor superfamily member 13C, B Cell-activating factor receptor, BAFF receptor, BLyS receptor 3, CD268) (APC) | US Biological 043073-APC product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

TNFRSF13C, NT (TNFRSF13C, BAFFR, BR3, Tumor necrosis factor receptor superfamily member 13C, B Cell-activating factor receptor, BAFF receptor, BLyS receptor 3, CD268) (APC)

catalog :

043073-APC

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

APC

reactivity :

human

product information

Catalog Number :

043073-APC

Product wo Prefix :

TNFRSF13C, NT (TNFRSF13C, BAFFR, BR3, Tumor necrosis factor receptor superfamily member 13C, B Cell-activating factor receptor, BAFF receptor, BLyS receptor 3, CD268) (APC)

Host :

rabbit

Product Type :

Pab

Conjugate :

APC

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. Applications: Suitable for use in Western Blot and FLISA. Other applications have not been tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

TNFRSF13C, BAFFR, BR3, Tumor necrosis factor receptor superfamily member 13C, B-cell-activating factor receptor, BAFF receptor, BLyS receptor 3, CD268

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1-30 in the N-terminal region of human TNFRSF13C., UniProt Accession #Q96RJ3.

Specificity :

Recognizes human TNFRSF13C.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1-30 in the N-terminal region of human TNFRSF13C., UniProt Accession #Q96RJ3. Specificity: Recognizes human TNFRSF13C. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FL WB

Storage Temperature :

4°C Do Not Freeze

Reference :

1. Mihalcik, S.A., et al. J. Immunol. 185(2):1045-1054(2010) 2. Parameswaran, R., et al. Cancer Res. 70(11):4346-4356(2010) 3. Davila, S., et al. Genes Immun. 11(3):232-238(2010) 4. Yuan, H., et al. DNA Cell Biol. 29(3):133-139(2010) 5. Yuan, H.X., et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 26(2):111-114(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/3/043073-APC_1.png