TLR4, ID (TLR4, Toll-like receptor 4, hToll, CD284) | US Biological 042879 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

TLR4, ID (TLR4, Toll-like receptor 4, hToll, CD284)

catalog :

042879

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

042879

Product wo Prefix :

TLR4, ID (TLR4, Toll-like receptor 4, hToll, CD284)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Applications: Suitable for use in Western Blot, Flow Cytometry and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

TLR4, Toll-like receptor 4, hToll, CD284

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 669-698 in the central region of human TLR4. Species Sequence Homology: bovine, hamster, porcine, and equine.

Specificity :

Recognizes human TLR4.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 669-698 in the central region of human TLR4. Species Sequence Homology: bovine, hamster, porcine, and equine. Specificity: Recognizes human TLR4. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E FC WB

Storage Temperature :

-20°C

Reference :

Sam-Agudu, N.A., et al. Am. J. Trop. Med. Hyg. 82(4):548-555(2010) Palomino-Morales, R.J., et al. Arthritis Res. Ther. 12 (2), R51 (2010) Rigoli, L., et al. Anticancer Res. 30(2):513-517(2010) da Silva Correia, J., et al. J. Biol. Chem. 277(3):1845-1854(2002) Shimazu, R., et al. J. Exp. Med. 189(11):1777-1782(1999)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/43/042879_1.jpg