TLR4, ID (TLR4, Toll-like receptor 4, hToll, CD284) (AP) | US Biological 042879-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

TLR4, ID (TLR4, Toll-like receptor 4, hToll, CD284) (AP)

catalog :

042879-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

042879-AP

Product wo Prefix :

TLR4, ID (TLR4, Toll-like receptor 4, hToll, CD284) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

TLR4, Toll-like receptor 4, hToll, CD284

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 669-698 in the central region of human TLR4, UniProt Accession: #O00206. Species Sequence Homology: bovine, hamster, porcine, equine

Specificity :

Recognizes human TLR4.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 669-698 in the central region of human TLR4, UniProt Accession: #O00206. Species Sequence Homology: bovine, hamster, porcine, equine Specificity: Recognizes human TLR4. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Sam-Agudu, N.A., et al. Am. J. Trop. Med. Hyg. 82(4):548-555(2010) Palomino-Morales, R.J., et al. Arthritis Res. Ther. 12 (2), R51 (2010) Rigoli, L., et al. Anticancer Res. 30(2):513-517(2010) da Silva Correia, J., et al. J. Biol. Chem. 277(3):1845-1854(2002) Shimazu, R., et al. J. Exp. Med. 189(11):1777-1782(1999)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/48/042879-AP_1.jpg