TGFB1, NT (TGFB1, TGFB, Transforming growth factor beta-1, Latency-associated peptide)

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product summary

company name :

US Biological

product type :

antibody

product name :

TGFB1, NT (TGFB1, TGFB, Transforming growth factor beta-1, Latency-associated peptide)

catalog :

042777

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

042777

Product wo Prefix :

TGFB1, NT (TGFB1, TGFB, Transforming growth factor beta-1, Latency-associated peptide)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

TGFB1 is a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. Applications: Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50 Immunofluorescence: 1:10-50 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mo

Alternate Name :

TGFB1, TGFB, Transforming growth factor beta-1, Latency-associated peptide

Immunogen :

TGFB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human TGFB1.

Specificity :

Human, mouse

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: TGFB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human TGFB1. Specificity: Human, mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IF IHC WB

Storage Temperature :

-20°C

Reference :

Perez, A.B., et al. Hum. Immunol. 71(11):1135-1140(2010) Xu, Z., et al. Biochem. Biophys. Res. Commun. 401(3):376-381(2010) Bran, G.M., et al. Anticancer Res. 30(9):3459-3463(2010) Zauli, G., et al. Blood 80(12):3036-3043(1992) Wrana, J.L., et al. Cell 71(6):1003-1014(1992)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/27/042777_1.jpg