TFAM, CT (TFAM, TCF6, TCF6L2, Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, Transcription factor 6-like 2)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

TFAM, CT (TFAM, TCF6, TCF6L2, Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, Transcription factor 6-like 2)

catalog :

042756

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

042756

Product wo Prefix :

TFAM, CT (TFAM, TCF6, TCF6L2, Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, Transcription factor 6-like 2)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells. Applications: Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Flow Cytometry: 1:10-50 Immunofluorescence: 1:10-50 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

TFAM, TCF6, TCF6L2, Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, Transcription factor 6-like 2

Immunogen :

TFAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-254 amino acids from the C-terminal region of human TFAM.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: TFAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-254 amino acids from the C-terminal region of human TFAM. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E FC IF IHC WB

Storage Temperature :

-20°C

Reference :

Wang, W., et al. Nucleic Acids Res. (2010) In press : Corneveaux, J.J., et al. Hum. Mol. Genet. 19(16):3295-3301(2010) Akhmetov, I.I., et al. Fiziol Cheloveka 36(2):121-125(2010) Shulman, J.M., et al. PLoS ONE 5 (6), E11244 (2010) : Laumet, G., et al. J. Alzheimers Dis. 20(4):1181-1188(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/11/042756_1.jpg

Picture4 Text :

TFAM Antibody (C-term) western blot analysis in Hela,Jurkat,K562,MCF-7 cell line lysates (35ug/lane).This demonstrates the TFAM antibody detected the TFAM protein (arrow).