TFAM, CT (TFAM, TCF6, TCF6L2, Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, Transcription factor 6-like 2) (AP) | US Biological 042756-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

TFAM, CT (TFAM, TCF6, TCF6L2, Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, Transcription factor 6-like 2) (AP)

catalog :

042756-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

042756-AP

Product wo Prefix :

TFAM, CT (TFAM, TCF6, TCF6L2, Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, Transcription factor 6-like 2) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells. Applications: Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 1:10-50 Immunofluorescence: 1:10-50 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

TFAM, TCF6, TCF6L2, Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, Transcription factor 6-like 2

Immunogen :

TFAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-254 amino acids from the C-terminal region of human TFAM.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: TFAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-254 amino acids from the C-terminal region of human TFAM. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IF IHC WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Wang, W., et al. Nucleic Acids Res. (2010) In press : Corneveaux, J.J., et al. Hum. Mol. Genet. 19(16):3295-3301(2010) Akhmetov, I.I., et al. Fiziol Cheloveka 36(2):121-125(2010) Shulman, J.M., et al. PLoS ONE 5 (6), E11244 (2010) : Laumet, G., et al. J. Alzheimers Dis. 20(4):1181-1188(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/16/042756-AP_1.jpg

Picture4 Text :

TFAM Antibody (C-term) western blot analysis in Hela,Jurkat,K562,MCF-7 cell line lysates (35ug/lane).This demonstrates the TFAM antibody detected the TFAM protein (arrow).