TAPBP, NT (TAPBP, NGS17, TAPA, Tapasin, NGS-17, TAP-associated protein, TAP-binding protein) (AP) | US Biological 042598-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

TAPBP, NT (TAPBP, NGS17, TAPA, Tapasin, NGS-17, TAP-associated protein, TAP-binding protein) (AP)

catalog :

042598-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

042598-AP

Product wo Prefix :

TAPBP, NT (TAPBP, NGS17, TAPA, Tapasin, NGS-17, TAP-associated protein, TAP-binding protein) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

TAPBP, NGS17, TAPA, Tapasin, NGS-17, TAP-associated protein, TAP-binding protein

Immunogen :

TAPBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human TAPBP.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: TAPBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human TAPBP. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Jiang, Q., et al. Tumour Biol. 31(5):451-459(2010) Rizvi, S.M., et al. Traffic 11(3):332-347(2010) Praveen, P.V., et al. Eur. J. Immunol. 40(1):214-224(2010) Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) : Lindquist, J.A., et al. EMBO J. 17(8):2186-2195(1998)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/40/042598-AP_1.jpg