STIM1, CT (STIM1, GOK, Stromal interaction molecule 1) | US Biological 042393 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

STIM1, CT (STIM1, GOK, Stromal interaction molecule 1)

catalog :

042393

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

042393

Product wo Prefix :

STIM1, CT (STIM1, GOK, Stromal interaction molecule 1)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

STIM1, GOK, Stromal interaction molecule 1

Immunogen :

STIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-546 amino acids from the C-terminal region of human STIM1.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: STIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-546 amino acids from the C-terminal region of human STIM1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Reference :

Byun, M., et al. J. Exp. Med. 207(11):2307-2312(2010) Park, C.Y., et al. Science 330(6000):101-105(2010) Walsh, C.M., et al. Biochem. J. 430(3):453-460(2010) Hawkins, B.J., et al. J. Cell Biol. 190(3):391-405(2010) Woodward, O.M., et al. PLoS ONE 5 (8), E12305 (2010) :

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/47/042393_1.jpg