STAU1, NT (STAU1, STAU, Double-stranded RNA-binding protein Staufen homolog 1) (AP) | US Biological 042386-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

STAU1, NT (STAU1, STAU, Double-stranded RNA-binding protein Staufen homolog 1) (AP)

catalog :

042386-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

042386-AP

Product wo Prefix :

STAU1, NT (STAU1, STAU, Double-stranded RNA-binding protein Staufen homolog 1) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

STAU1, STAU, Double-stranded RNA-binding protein Staufen homolog 1

Immunogen :

STAU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 26-55 amino acids selected from the N-terminal region of human STAU1.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: STAU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 26-55 amino acids selected from the N-terminal region of human STAU1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

4°C Do Not Freeze

Reference :

de Lucas, S., et al. J. Virol. 84(15):7603-7612(2010) Martel, C., et al. RNA 16(3):585-597(2010) Abrahamyan, L.G., et al. J. Cell. Sci. 123 (PT 3), 369-383 (2010) : Milev, M.P., et al. Retrovirology 7, 41 (2010) : Weidensdorfer, D., et al. RNA 15(1):104-115(2009)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/15/042386-AP_1.jpg