SQSTM1, phosphorylated (S403) (SQSTM1, ORCA, OSIL, Sequestosome-1, EBI3-associated protein of 60kD, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62kD, Ubiquitin-binding protein p62)

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product summary

company name :

US Biological

product type :

antibody

product name :

SQSTM1, phosphorylated (S403) (SQSTM1, ORCA, OSIL, Sequestosome-1, EBI3-associated protein of 60kD, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62kD, Ubiquitin-binding protein p62)

catalog :

042284

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human

product information

Catalog Number :

042284

Product wo Prefix :

SQSTM1, phosphorylated (S403) (SQSTM1, ORCA, OSIL, Sequestosome-1, EBI3-associated protein of 60kD, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62kD, Ubiquitin-binding protein p62)

Host :

rabbit

Product Type :

Pab

Antigen Modification :

phosphorylated

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. Applications: Suitable for use in Dot Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Dot blot 1:500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

SQSTM1, ORCA, OSIL, Sequestosome-1, EBI3-associated protein of 60kD, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62kD, Ubiquitin-binding protein p62

Immunogen :

SQSTM1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S403 of human SQSTM1.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: SQSTM1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S403 of human SQSTM1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

DB E

Storage Temperature :

-20°C

Reference :

Visconti, M.R., et al. J. Bone Miner. Res. 25(11):2368-2373(2010) Ding, W.X., et al. J. Biol. Chem. 285(36):27879-27890(2010) Gao, C., et al. Nat. Cell Biol. 12(8):781-790(2010) Jain, A., et al. J. Biol. Chem. 285(29):22576-22591(2010) Lau, A., et al. Mol. Cell. Biol. 30(13):3275-3285(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/44/042284_1.jpg