SPOP, NT (SPOP, Speckle-type POZ protein, HIB homolog 1, Roadkill homolog 1) (AP) | US Biological 042252-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

SPOP, NT (SPOP, Speckle-type POZ protein, HIB homolog 1, Roadkill homolog 1) (AP)

catalog :

042252-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

042252-AP

Product wo Prefix :

SPOP, NT (SPOP, Speckle-type POZ protein, HIB homolog 1, Roadkill homolog 1) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq]. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

SPOP, Speckle-type POZ protein, HIB homolog 1, Roadkill homolog 1

Immunogen :

SPOP antibody is generated from rabbits immunized with a KLH conjugated synthetic between 85-115 amino acids selected from the N-terminal region of human SPOP.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: SPOP antibody is generated from rabbits immunized with a KLH conjugated synthetic between 85-115 amino acids selected from the N-terminal region of human SPOP. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Rose, J. Phd, et al. Mol. Med. (2010) In press : Zhuang, M., et al. Mol. Cell 36(1):39-50(2009) Liu, J., et al. Science 323(5918):1218-1222(2009) Bunce, M.W., et al. J. Biol. Chem. 283(13):8678-8686(2008) Byun, B., et al. Biofactors 31 (3-4), 165-169 (2007) :

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/22/042252-AP_1.jpg