Sox2, phosphorylated (S246) (SOX2, Transcription factor SOX-2) (APC) | US Biological 042166-APC product information

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product summary

company name :

US Biological

product type :

antibody

product name :

Sox2, phosphorylated (S246) (SOX2, Transcription factor SOX-2) (APC)

catalog :

042166-APC

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

APC

antigen modification :

phosphorylated

reactivity :

human

product information

Catalog Number :

042166-APC

Product wo Prefix :

Sox2, phosphorylated (S246) (SOX2, Transcription factor SOX-2) (APC)

Host :

rabbit

Product Type :

Pab

Conjugate :

APC

Antigen Modification :

phosphorylated

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Applications: Suitable for use in Immunofluorescence, Dot Blot and ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Allophycocyanin (APC) is light sensitive. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

SOX2, Transcription factor SOX-2

Immunogen :

KLH-conjugated synthetic phospho-peptide mapping to a fragment of residues surrounding S246 of human Sox2, UniProt Accession #P48431. Species sequence homology: mouse

Specificity :

Recognizes human Sox2.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic phospho-peptide mapping to a fragment of residues surrounding S246 of human Sox2, UniProt Accession #P48431. Species sequence homology: mouse Specificity: Recognizes human Sox2. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

DB FL IF

Storage Temperature :

4°C Do Not Freeze

Reference :

1. Gen, Y., et al. Cancer Genet. Cytogenet. 202(2):82-93(2010) 2. Ji, J., et al. Hum. Pathol. 41(10):1438-1447(2010) 3. Fang, X., et al. OMICS 14(4):369-384(2010) 4. Sholl, L.M., et al. Am. J. Surg. Pathol. 34(8):1193-1198(2010) 5. Zhang, D., et al. BMC Med. Genet. 11, 116 (2010) :

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/17/042166-APC_1.png