Sox2, phosphorylated (pS249) (SOX2, Transcription factor SOX-2) | US Biological 042164 product information

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product summary

company name :

US Biological

product type :

antibody

product name :

Sox2, phosphorylated (pS249) (SOX2, Transcription factor SOX-2)

catalog :

042164

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human

product information

Catalog Number :

042164

Product wo Prefix :

Sox2, phosphorylated (pS249) (SOX2, Transcription factor SOX-2)

Host :

rabbit

Product Type :

Pab

Antigen Modification :

phosphorylated

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Applications: Suitable for use in Dot Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Dot blot 1:500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

SOX2, Transcription factor SOX-2

Immunogen :

phospho-Sox2-pS249 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between amino acids 230-260 surrounding S249 of human Sox2.

Specificity :

Human

Purity :

Purified by peptide immunoaffinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by peptide immunoaffinity chromatography. Immunogen: phospho-Sox2-pS249 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between amino acids 230-260 surrounding S249 of human Sox2. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

DB E

Storage Temperature :

-20°C

Reference :

Tung, C.L., et al. Biochem. Biophys. Res. Commun. 393(3):420-425(2010) Laga, A.C., et al. Am. J. Pathol. 176(2):903-913(2010) Gu, H.F., et al. Gend Med 6(4):555-564(2009) Schneider, A., et al. Am. J. Med. Genet. A 149A (12), 2706-2715 (2009) : Zhang, X., et al. Mol. Vis. 15, 2911-2918 (2009) : Gure, A.O., et al. Proc. Natl. Acad. Sci. U.S.A. 97(8):4198-4203(2000) Kamachi, Y., et al. Trends Genet. 16(4):182-187(2000) Helland, R., et al. Acta Crystallogr. D Biol. Crystallogr. 55 (PT 1), 139-148 (1999) : Yuan, H., et al. Genes Dev. 9(21):2635-2645(1995) Stevanovic, M., et al. Mamm. Genome 5(10):640-642(1994)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/30/042164_1.jpg