Siglec 5, NT (Siglec 5, CD33L2, OBBP2, Sialic acid-binding Ig-like lectin 5, CD33 antigen-like 2, Obesity-binding protein 2, CD170)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Siglec 5, NT (Siglec 5, CD33L2, OBBP2, Sialic acid-binding Ig-like lectin 5, CD33 antigen-like 2, Obesity-binding protein 2, CD170)

catalog :

041737

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

041737

Product wo Prefix :

Siglec 5, NT (Siglec 5, CD33L2, OBBP2, Sialic acid-binding Ig-like lectin 5, CD33 antigen-like 2, Obesity-binding protein 2, CD170)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

The sialic acid-binding immunoglobulin-like lectins (SIGLECs), such as SIGLEC5, are a subgroup of the immunoglobulin (Ig) superfamily that mediate protein-carbohydrate interactions. They specifically interact with sialic acids in glycoproteins and glycolipids, with each SIGLEC having a particular preference for both the nature of the sialic acid and its glycosidic linkage to adjacent sugars. SIGLECs have similar structures, including extracellular Ig-like domains composed of an N-terminal V-set domain followed by varying numbers of C2-set domains. It appears that all SIGLECs have an unusual arrangement of conserved cysteine residues in the V-set and adjacent C2-set domains. Most SIGLECs are expressed uniquely within the hematopoietic system (Cornish et al., 1998 [PubMed 9731071]). Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

SIGLEC5, CD33L2, OBBP2, Sialic acid-binding Ig-like lectin 5, CD33 antigen-like 2, Obesity-binding protein 2, CD170

Immunogen :

SIGLEC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the N-terminal region of human SIGLEC5.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: SIGLEC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the N-terminal region of human SIGLEC5. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Soto, P.C., et al. J. Immunol. 184(8):4185-4195(2010) Davila, S., et al. Genes Immun. 11(3):232-238(2010) Carlin, A.F., et al. J. Exp. Med. 206(8):1691-1699(2009) Zhuravleva, M.A., et al. J. Mol. Biol. 375(2):437-447(2008) Gunnarsson, P., et al. FASEB J. 21(14):4059-4069(2007)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/4/041737_1.jpg