SERPINE1, ID (SERPINE1, PAI1, PLANH1, Plasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor, Serpin E1)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

SERPINE1, ID (SERPINE1, PAI1, PLANH1, Plasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor, Serpin E1)

catalog :

041585

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

041585

Product wo Prefix :

SERPINE1, ID (SERPINE1, PAI1, PLANH1, Plasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor, Serpin E1)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Applications: Suitable for use in Western Blot, Flow Cytometry and ELISA. Other applications have not been tested. Recommended Dilutions: Western Blot: 1:1000 Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

SERPINE1, PAI1, PLANH1, Plasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor, Serpin E1

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 188-216 in the central region of human SERPINE1.

Specificity :

Recognizes human SERPINE1.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As Reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 188-216 in the central region of human SERPINE1. Specificity: Recognizes human SERPINE1. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E FC WB

Storage Temperature :

-20°C

Reference :

1. Ma, Z., et al. Biochem. Biophys. Res. Commun. 400(4):569-574 (2010). 2. Ince, D.A., et al. Genet Test Mol Biomarkers 14(5):643-647 (2010). 3. Bern, M.M., et al. Clin. Appl. Thromb. Hemost. 16(5):574-578 (2010). 4. Markl, B., et al. J Surg Oncol 102(3):235-241 (2010). 5. de Haas, E.C., et al. Cancer (2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/9/041585_1.pdf