antibody

S100B, ID (S100B, Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B) (AP)

041358-AP

200 ul

polyclonal

domestic rabbit

AP

S100B, ID (S100B, Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B) (AP)

rabbit

Pab

AP

Antibodies

200 ul

IgG

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Hu

S100B, Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 28-56 in the central region of human S100B/S-10, UniProt Accession #P04271. Species Sequence Homology: bovine, mouse, rabbit and rat

Recognizes human S100B/S-10.

Purified by Protein A affinity chromatography.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

As Reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 28-56 in the central region of human S100B/S-10, UniProt Accession #P04271. Species Sequence Homology: bovine, mouse, rabbit and rat Specificity: Recognizes human S100B/S-10. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E WB

4°C Do Not Freeze

1. Sahoo, N., et al. FEBS Lett. 584(18):3896-3900(2010). 2. Lin, J., et al. J. Biol. Chem. 285(35):27487-27498(2010). 3. van Dieck, J., et al. FEBS Lett. 584(15):3269-3274(2010). 4. Egberts, F., et al. Anticancer Res. 30(5):1799-1805(2010). 5. Boutsikou, T., et al. Mediators Inflamm. 2010, 790605 (2010) :

https://usbio-images.r.worldssl.net/prodimages/9/041358-AP_1.jpg