RPA1, CT (RPA1, REPA1, RPA70, Replication protein A 70kD DNA-binding subunit, Replication factor A protein 1, Single-stranded DNA-binding protein)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

RPA1, CT (RPA1, REPA1, RPA70, Replication protein A 70kD DNA-binding subunit, Replication factor A protein 1, Single-stranded DNA-binding protein)

catalog :

041173

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

041173

Product wo Prefix :

RPA1, CT (RPA1, REPA1, RPA70, Replication protein A 70kD DNA-binding subunit, Replication factor A protein 1, Single-stranded DNA-binding protein)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

RPA1 plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing. Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

RPA1, REPA1, RPA70, Replication protein A 70kD DNA-binding subunit, Replication factor A protein 1, Single-stranded DNA-binding protein

Immunogen :

RPA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-559 amino acids from the C-terminal region of human RPA1.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: RPA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-559 amino acids from the C-terminal region of human RPA1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Choi, J.H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(31):13660-13665(2010) Locatelli, G.A., et al. Biochem. J. 429(3):573-582(2010) Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010) Guillem, V.M., et al. Am. J. Hematol. 85(7):482-486(2010) Oakley, G.G., et al. Front. Biosci. 15, 883-900 (2010) :

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/26/041173_1.jpg