ROR1, NT (ROR1, NTRKR1, Tyrosine-protein kinase transmembrane receptor ROR1, Neurotrophic tyrosine kinase, receptor-related 1)

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product summary

company name :

US Biological

product type :

antibody

product name :

ROR1, NT (ROR1, NTRKR1, Tyrosine-protein kinase transmembrane receptor ROR1, Neurotrophic tyrosine kinase, receptor-related 1)

catalog :

041167

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

041167

Product wo Prefix :

ROR1, NT (ROR1, NTRKR1, Tyrosine-protein kinase transmembrane receptor ROR1, Neurotrophic tyrosine kinase, receptor-related 1)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

ROR1 is a receptor protein tyrosine kinase whose cellular role has not been determined. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors. Studies of a similar protein in mouse suggest that this protein may interact with another receptor protein tyrosine kinase and may be involved in skeletal and cardiac development. ROR1 is expressed strongly in human heart, lung and kidney, but weakly in the CNS. Short isoform is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. Applications: Suitable for use in Western Blot and Flow Cytometry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Flow Cytometry: 1:10-50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

ROR1, NTRKR1, Tyrosine-protein kinase transmembrane receptor ROR1, Neurotrophic tyrosine kinase, receptor-related 1

Immunogen :

Synthetic peptide corresponding to a portion of amino acids within aa40-69 from the N-terminal region of human ROR1 conjugated to KLH (Q01973).

Specificity :

Recognizes human ROR1 at ~104kD.

Purity :

Purified by ammonium sulfate precipitation and dialysis.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by ammonium sulfate precipitation and dialysis. Immunogen: Synthetic peptide corresponding to a portion of amino acids within aa40-69 from the N-terminal region of human ROR1 conjugated to KLH (Q01973). Specificity: Recognizes human ROR1 at ~104kD. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FC WB

Storage Temperature :

-20°C

Reference :

1. Nomi, M., et al., Mol. Cell. Biol. 21(24): 8329-8335 (2001). 2. Reddy, U.R., et al., Genomics 41(2): 283-285 (1997). 3. Reddy, U.R., et al., Oncogene 13(7): 1555-1559 (1996). 4. Masiakowski, P., et al., J. Biol. Chem. 267(36): 26,181-26,190 (1992).

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/45/041167_1.jpg