RET (RET, CDHF12, CDHR16, PTC, RET51, Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret, Soluble RET kinase fragment, Extracellular cell-membrane anchored RET cadherin 120kD fragment)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

RET (RET, CDHF12, CDHR16, PTC, RET51, Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret, Soluble RET kinase fragment, Extracellular cell-membrane anchored RET cadherin 120kD fragment)

catalog :

040964

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

040964

Product wo Prefix :

URL USB :

www.usbio.net/antibodies/040964/RET-RET-CDHF12-CDHR16-PTC-RET51-Protooncogene-tyrosineprotein-kinase-receptor-Ret-Cadherin-family-member-12-Protooncogene-cRet-Soluble-RET-kinase-fragment-Extracellular-cellmembrane-anchored-RET-cadherin-120kD-fragment

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. Applications:. Suitable for use in Western Blot, ELISA. Recommended Dilution:. ELISA: 1:1,000. Western Blot: 1:50-100. Storage and Stability:. May be stored at 4 C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

RET, CDHF12, CDHR16, PTC, RET51, Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret, Soluble RET kinase fragment, Extracellular cell-membrane anchored RET cadherin 120kD fragment

Immunogen :

RET antibody is generated from rabbits immunized with His fusion protein of human RET.

Specificity :

Human

Purity :

Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab. Isotype: IgG. Host: rabbit. Source: human. Concentration: As reported. Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS. Immunogen: RET antibody is generated from rabbits immunized with His fusion protein of human RET. Specificity: Human. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20 C

Reference :

Siqueira, D.R., et al. Endocr. Relat. Cancer 17(4):953-963(2010) Gockel, H.R., et al. Hum. Genet. 128(4):353-364(2010) Kim, H.K., et al. Anticancer Res. 30(9):3621-3627(2010) Pacini, F., et al. Clin Oncol (R Coll Radiol) 22(6):475-485(2010) Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :

Picture 1 File Name :

usbio-images.r.worldssl.net/prodimages/6/040964_1.jpg