RARA, CT (RARA, NR1B1, Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1) (APC) | US Biological 040836-APC product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

RARA, CT (RARA, NR1B1, Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1) (APC)

catalog :

040836-APC

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

APC

reactivity :

human

product information

Catalog Number :

040836-APC

Product wo Prefix :

RARA, CT (RARA, NR1B1, Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1) (APC)

Host :

rabbit

Product Type :

Pab

Conjugate :

APC

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus. Applications: Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry and FLISA. Other applications have not been tested. Recommended Dilution: Immunohistochemistry: Formalin fixed paraffin embedded sections Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Hu Mo

Alternate Name :

RARA, NR1B1, Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 322-349 in the C-terminal region of human RARA.

Specificity :

Recognizes human RARA. Species Crossreactivity: mouse

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Concentration :

As Reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 322-349 in the C-terminal region of human RARA. Specificity: Recognizes human RARA. Species Crossreactivity: mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FC FL IF IHC WB

Storage Temperature :

4°C Do Not Freeze

Reference :

1. Park, U.H., et al. J. Biol. Chem. 285(44):34269-34278(2010) 2. Asleson, A.D., et al. Cancer Genet. Cytogenet. 202(1):33-37(2010) 3. Catalano, A., et al. Blood 110(12):4073-4076(2007) 4. Wells, R.A., et al. Nat. Genet. 17(1):109-113(1997) 5. Chen, Z., et al. Proc. Natl. Acad. Sci. U.S.A. 91(3):1178-1182(1994)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/24/040836-APC_1.jpg

Picture4 Text :

Confocal immunofluorescent analysis with MCF-7 cells using 040836 followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Picture 5 File Name :

https://usbio-images.r.worldssl.net/prodimages/24/040836-APC_5.png

Picture5 Text :

Flow Cytometry analysis of Hela cells (right histogram) using 040836 compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.