RAMP3, CT (RAMP3, Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3)

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product summary

company name :

US Biological

product type :

antibody

product name :

RAMP3, CT (RAMP3, Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3)

catalog :

040819

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

040819

Product wo Prefix :

RAMP3, CT (RAMP3, Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilution: Western Blot: 1:2000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mo

Alternate Name :

RAMP3, Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 90-118 in the C-terminal region of human RAMP3, UniProt Accession # O60896.

Specificity :

Recognizes human RAMP3. Species Crossreactivity: mouse

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 90-118 in the C-terminal region of human RAMP3, UniProt Accession # O60896. Specificity: Recognizes human RAMP3. Species Crossreactivity: mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) 2. Bailey, R.J., et al. Peptides 31(4):579-584(2010) 3. Harikumar, K.G., et al. Biochemistry 48(49):11773-11785(2009) 4. Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) 5. Kuwasako, K., et al. Biochem. Biophys. Res. Commun. 377(1):109-113(2008).

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/7/040819_1.png