PTPN2, CT (PTPN2, PTPT, Tyrosine-protein phosphatase non-receptor type 2, T-cell protein-tyrosine phosphatase)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

PTPN2, CT (PTPN2, PTPT, Tyrosine-protein phosphatase non-receptor type 2, T-cell protein-tyrosine phosphatase)

catalog :

040662

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

040662

Product wo Prefix :

PTPN2, CT (PTPN2, PTPT, Tyrosine-protein phosphatase non-receptor type 2, T-cell protein-tyrosine phosphatase)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Three alternatively spliced variants of this gene, which encode isoforms differing at their extreme C-termini, have been described. The different C-termini are thought to determine the substrate specificity, as well as the cellular localization of the isoforms. Two highly related but distinctly processed pseudogenes that localize to distinct chromosomes have been reported. [provided by RefSeq]. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

PTPN2, PTPT, Tyrosine-protein phosphatase non-receptor type 2, T-cell protein-tyrosine phosphatase

Immunogen :

PTPN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-358 amino acids from the C-terminal region of human PTPN2.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: PTPN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-358 amino acids from the C-terminal region of human PTPN2. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Reference :

Scharl, M., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (4), G935-G945 (2010) : Morgan, A.R., et al. Tissue Antigens 76(2):119-125(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Kleppe, M., et al. Nat. Genet. 42(6):530-535(2010) Amre, D.K., et al. Aliment. Pharmacol. Ther. 31(11):1186-1191(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/32/040662_1.jpg