PRMT4, CT (Protein Arginine N-Methyltransferase 4, CARM1) (Biotin) | US Biological 040470-Biotin product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

PRMT4, CT (Protein Arginine N-Methyltransferase 4, CARM1) (Biotin)

catalog :

040470-Biotin

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

biotin

reactivity :

human

product information

Catalog Number :

040470-Biotin

Product wo Prefix :

PRMT4, CT (Protein Arginine N-Methyltransferase 4, CARM1) (Biotin)

Host :

rabbit

Product Type :

Pab

Conjugate :

Biotin

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50 Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

Protein Arginine N-Methyltransferase 4, CARM1

Immunogen :

PRMT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PRMT4.

Specificity :

Human

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin. Purity: Purified by Protein G affinity chromatography. Immunogen: PRMT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PRMT4. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Reference :

Wada K, et al. Biochim Biophys Acta. 2002. 1591:1. Cimato TR, et al. J Neurosci Res. 2002. 67:435. Frankel A, et al. J Biol Chem. 2002. 277:3537. Brahms H, et al. RNA. 2001. 7:1531. Pelletier M, et al. Mol Biochem Parasitol. 2001. 118:49. Belyanskaya LL, et al. J Biol Chem. 2001. 276:18681. Rho J, et al. J Biol Chem. 2001. 276:11393. Scorilas A, et al. Biochem Biophys Res Commun. 2000. 278:349. Frankel A, et al. J Biol Chem. 2000. 275:32974. Zhang X, et al. EMBO J. 19:3509. Tang J, et al. J Biol Chem. 1998. 273:16935.