PLK1, CT (PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

PLK1, CT (PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13)

catalog :

040171

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

040171

Product wo Prefix :

PLK1, CT (PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Applications: Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after recept. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 573-603 in the C-terminal region of human PLK1, UniProt Accession #P53350; Q07832. Species Sequence Homology: mouse

Specificity :

Recognizes human PLK1.

Purity :

Purified by ammonium sulfate precipitation

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As Reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by ammonium sulfate precipitation Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 573-603 in the C-terminal region of human PLK1, UniProt Accession #P53350; Q07832. Species Sequence Homology: mouse Specificity: Recognizes human PLK1. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Reference :

1. Ree, A.H., et al., Oncogene 22(55):8952-8955 (2003). 2. Cheng, K.Y., et al., EMBO J. 22(21):5757-5768 (2003). 3. Elia, A.E., et al., Cell 115(1):83-95 (2003). 4. Lin, H.R., et al., J. Biol. Chem. 278(38):35979-35987 (2003). 5. Neef, R., et al., J. Cell Biol. 162(5):863-875 (2003).

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/11/040171_1.jpg